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E3 ligase Ligand 8
CAS No. 1225383-33-4
E3 ligase Ligand 8( —— )
Catalog No. M23396 CAS No. 1225383-33-4
E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 32 | In Stock |
|
| 10MG | 50 | In Stock |
|
| 25MG | 102 | In Stock |
|
| 50MG | 170 | In Stock |
|
| 100MG | 282 | In Stock |
|
| 500MG | 691 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameE3 ligase Ligand 8
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NoteResearch use only, not for human use.
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Brief DescriptionE3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs.
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DescriptionE3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1225383-33-4
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Formula Weight530.61
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Molecular FormulaC31H34N2O6
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Purity>98% (HPLC)
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SolubilityDMSO: 90 mg/mL (169.62 mM; Need ultrasonic)
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SMILESCC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC4=CC=CC=C4)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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