E3 ligase Ligand 8

CAS No. 1225383-33-4

E3 ligase Ligand 8 ( —— )

Catalog No. M23396 CAS No. 1225383-33-4

E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 32 In Stock
10MG 50 In Stock
25MG 102 In Stock
50MG 170 In Stock
100MG 282 In Stock
500MG 691 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    E3 ligase Ligand 8
  • Note
    Research use only, not for human use.
  • Brief Description
    E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs.
  • Description
    E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1225383-33-4
  • Formula Weight
    530.6
  • Molecular Formula
    C31H34N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 90 mg/mL (169.62 mM; Need ultrasonic)
  • SMILES
    CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC4=CC=CC=C4)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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