E3 ligase Ligand 8 ( —— )

Catalog No. M23396 CAS No. 1225383-33-4

E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	32	In Stock
10MG	50	In Stock
25MG	102	In Stock
50MG	170	In Stock
100MG	282	In Stock
500MG	691	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

E3 ligase Ligand 8
Note

Research use only, not for human use.
Brief Description

E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs.
Description

E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

1225383-33-4
Formula Weight

530.6
Molecular Formula

C31H34N2O6
Purity

>98% (HPLC)
Solubility

DMSO: 90 mg/mL (169.62 mM; Need ultrasonic)
SMILES

CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC4=CC=CC=C4)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

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